Vascular Smooth Muscle Cells Ablation with Endovascular Nonthermal Irreversible Electroporation
نویسندگان
چکیده
منابع مشابه
Non Thermal Irreversible Electroporation: Novel Technology for Vascular Smooth Muscle Cells Ablation
BACKGROUND Non thermal Irreversible electroporation (NTIRE) is a new tissue ablation method that induces selective damage only to the cell membrane while sparing all other tissue components. Our group has recently showed that NTIRE attenuated neointimal formation in rodent model. The goal of this study was to determine optimal values of NTIRE for vascular smooth muscle cell (VSMC) ablation. M...
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Exposing biological cells to sufficiently strong external electric fields causes electroporation of cell membranes, i.e. occurrence of transient or permanent permeable pathways between the interior and exterior of the cell. Electroporation can be used to introduce various molecules into cells (reversible electroporation) or to kill cells (irreversible electroporation), which can in turn be used...
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BACKGROUND Ablation is increasingly used to treat primary and secondary liver cancer. Ablation near portal pedicles and hepatic veins is challenging. Irreversible electroporation (IRE) is a new ablation technique that does not rely on heat and, in animals, appears to be safe and effective when applied near hepatic veins and portal pedicles. This study evaluated the safety and short-term outcome...
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ژورنال
عنوان ژورنال: Journal of Vascular and Interventional Radiology
سال: 2010
ISSN: 1051-0443
DOI: 10.1016/j.jvir.2010.06.024